Meldonium – Meldronat 500 mg 60 caps

Meldonium is a compound that was developed by a Latvian chemist in the 1970s. It has an effect that improves cell metabolism and at the same time protects the heart, which is why we often encounter the agent in the treatment of cardiac disorders. Meldonium is used to treat cardiovascular diseases, cerebral ischemia and chronic fatigue syndrome. In addition, it has antioxidant and anti-inflammatory properties, which may improve physical and mental performance. Interestingly, meldonium also has a slight nootropic effect. Why is it so popular in the world of performance and endurance sports? What results can we expect from supplementation?

Meldonium what is it?

Meldonium is a chemical compound from the betaine group and a structural analogue of gamma-butyrobetaine (GBB). Carnitine is a substance that transports fatty acids to the mitochondria, where they are “burned” and converted into energy. Meldonium inhibits this process, which reduces the consumption of oxygen by cells and increases the production of nitric oxide. Nitric oxide dilates blood vessels and improves blood flow to the heart and brain. Thanks to this, meldonium can prevent or alleviate tissue hypoxia that may be caused by heart disease, stroke or exercise.

How does meldronat affect the heart?

• Heart Protection: has a cardioprotective effect, preventing the negative effects of myocardial hypoxia.
• Blood Pressure Stabilization: Regular use of meldonium helps in maintaining stable blood pressure.
• Increasing Tolerance to Physical Exercise: People with chronic heart failure experience improvement in their tolerance to physical exercise, and importantly, healthy people also experience positive changes.
• Arrhythmia Prevention: It can also prevent the occurrence of dangerous arrhythmias such as ventricular fibrillation.

How does it help the heart?

• Increased Blood Flow: By increasing blood flow, it helps meet the oxygen needs of the heart muscle.
• Improved Cardiac Contractility: Meldonium improves the contractility of the heart, which translates into more efficient pumping of blood.
• Reduction of the Risk of Heart Attack: In ischemic conditions, limits the area of ​​infarction by reducing the negative impact of hypoxia on the heart.

Meldonium 500 mg and running

Meldonium is often used by athletes, especially runners, as a performance enhancer. Mildronate may improve endurance, strength and speed in runners because it reduces muscle oxygen consumption and increases energy availability. The product may also protect the heart against damage caused by intense exercise.

Mechanism of Action
The substance works by dilating blood vessels, which increases blood flow and delivers oxygen to tissues. Additionally, it influences the effective use of fatty acids by the body.

Energy Utilization Optimization
Acting as a butyl betaine hydroxylase inhibitor, it leads to a reduction in intracellular carnitine levels. This, in turn, leads to optimization of the fatty acid oxidation process and increased production of ATP – the main energy carrier.

Meldonium during intense physical exercise
During intense physical exercise, when the body experiences hypoxia, it activates the anaerobic glycolysis pathway. This is energetically beneficial because it uses less oxygen than beta oxidation of fatty acids, leading to more available energy in the form of ATP.

Improving Aerobic Endurance and Cardiac Performance
Mildronate not only increases aerobic endurance, but also makes the heart work more efficiently, which translates into better performance during physical activity.

Meldronat is also a nootropic

Improved cognitive functions

One of the key benefits of using the substance is the support of cognitive functions such as memory and concentration. Thanks to this, when using the product, we can experience improvement in intellectual abilities and better concentration.

Supporting glucose metabolism in the brain

Meldonium additionally affects metabolic processes in the brain by increasing the oxidation of glucose, which is the main fuel for our brain. This increases the absorption of glucose by the nervous system, which translates into increased energy and optimal brain functioning.

How to take meldonium?

Typically, meldonium is taken once or twice a day. The dose is 500 to 1000 mg per day. Athletes use cyclic dosing lasting 6 weeks, followed by a 2-week break. (1 Meldronat capsule contains 500 mg of meldonium)

Meldronate will work well in combination with products such as GW501516.

What is worth remembering about meldonium 500 mg?

Mildronate has many medical applications, but also stimulating potential. It may help treat cardiovascular disease, cerebral ischemia and chronic fatigue syndrome, but it may also improve physical and mental performance in sports.

INTENDED FOR RESEARCH PURPOSES!
All the above-mentioned properties are observed in laboratory tests, not performed on humans, they are for information purposes only. All information contained in the descriptions has not been approved by GIS, GIF or EFSA. The substance is not a medicine, food product or dietary supplement and is therefore not suitable for human consumption. The product qualifies as a chemical reagent/reference material authorized for marketing in the EU. It can only be used for scientific research. Other information about the agent is included in the safety data sheet for the chemical substance, which we make available for viewing. Products are available only to institutions or private individuals associated with research or laboratory activities.

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