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MINDHUNTER – PHENYLPIRACETAM / ANIRACETAM / ALPHA-GPC – Nootropic Supplement

Mindhunter is an innovative nootropic supplement that contains aniracetam, phenylpiracetam, and alpha-GPC. Its formula has been developed based on scientific research and user experiences. What does it contain in its composition? Is it worth using Mindhunter? We answer all these questions in the text.

sklep suplement nootropowy alpha-gpc aniracetam phenylpiracetam

PHENYLPIRACETAM

Phenylpiracetam was created by Russian scientists for cosmonauts to support their cognitive functions, maintain alertness, and cope with psychological stress during long space flights.

It belongs to the racetam family of compounds, known for increasing acetylcholine production, improving brain blood flow, and associated benefits, making them useful in brain disorders and cognitive enhancement (1, 2).

It is known for its psychostimulant properties and increases physical activity (animal studies), indicating its stimulating potential. It increases energy levels, alertness, motivation, and reduces drowsiness to a greater extent than methylphenidate and amphetamine (3).

Phenylpiracetam’s energizing properties are so significant that many users report its effectiveness in increasing productivity and reducing fatigue more than modafinil, making it a potentially safer alternative that does not negatively impact brain neuroplasticity (4).

The main effects reported by users of phenylpiracetam include (5):

  • Improved focus
  • Increased motivation
  • Elevated energy levels

One notable use of phenylpiracetam is its ability to reverse some of the side effects of benzodiazepines (6, 7, 8, 9). Animal studies have shown that it increases instrumental behavior (increased motivation under load), inhibits nystagmus, and has anticonvulsant effects.

One of the most important effects of phenylpiracetam is its ability to bind to the dopamine transporter (DAT inhibitor) (10). This leads to an increased dopamine load and reinforcement of its signaling. Interestingly, similar mechanisms are used by banned stimulant substances like cocaine. However, in the case of phenylpiracetam, it has a neuroprotective and anti-inflammatory effect, partly due to its ability to improve brain blood flow. This is also associated with better oxygenation, increased transport of nutrients, and more efficient removal of metabolic waste products.

Phenylpiracetam’s unique action in increasing motivation and energy levels is due to its dopaminergic effects, including an increase in the density of dopamine D2 and D3 receptors (11,12).


ANIRACETAM

Aniracetam, belonging to the racetam family, is classified under the AMPAkin group, a category of nootropic compounds that regulate the function of AMPA receptors in the brain. These receptors are involved in glutamate neurotransmission and influence synaptic-level transmission. The result is enhanced stimulation but achieved through more efficient neuronal work, rather than stimulation, which can have certain side effects, such as irritability, as seen with caffeine.

It is a cholinergic substance, meaning that it leads to an increase in acetylcholine levels in the brain. It is known for its anxiolytic properties, reducing anxiety, and enhancing memory consolidation, as well as the ability to focus on tasks. Compounds of this type have a tendency to stimulate the nervous system without causing side effects like those associated with excessive caffeine consumption.

Aniracetam is derived from piracetam but differs significantly. Aniracetam is more accessible to the brain due to its lipophilicity (requiring fats for transport), whereas piracetam is soluble in water. Its effects are faster and shorter-lasting than piracetam. Interestingly, piracetam is largely metabolized by the liver, with only about 10% reaching the brain, while aniracetam has nearly 100% bioavailability in the body.

What other benefits does it provide?

In terms of its impact on the brain, both compounds support the learning process, the retention of information, and have neuroprotective effects (repairing damage to the brain). Aniracetam has additional benefits, such as reducing anxiety, facilitating dealing with fear, and reducing symptoms of depression [14]. Additionally, it improves social interactions. This is likely due to increased dopamine and serotonin activity in the brain (in the prefrontal cortex) indirectly through AMPA receptor stimulation.

“MINDHUNTER – PHENYLPIRACETAM / ANIRACETAM / ALPHA-GPC – Nootropic Supplement

Mindhunter is an innovative nootropic supplement that contains aniracetam, phenylpiracetam, and alpha-GPC. Its formula has been developed based on scientific research and user experiences. What does it contain in its composition? Is it worth using Mindhunter? We answer all these questions in the text. nootropic supplement store alpha-gpc aniracetam phenylpiracetam

PHENYLPIRACETAM

Phenylpiracetam was created by Russian scientists for cosmonauts to support their cognitive functions, maintain alertness, and cope with psychological stress during long space flights.

It belongs to the racetam family of compounds, known for increasing acetylcholine production, improving brain blood flow, and associated benefits, making them useful in brain disorders and cognitive enhancement (1, 2).

It is known for its psychostimulant properties and increases physical activity (animal studies), indicating its stimulating potential. It increases energy levels, alertness, motivation, and reduces drowsiness to a greater extent than methylphenidate and amphetamine (3).

Phenylpiracetam’s energizing properties are so significant that many users report its effectiveness in increasing productivity and reducing fatigue more than modafinil, making it a potentially safer alternative that does not negatively impact brain neuroplasticity (4). The main effects reported by users of phenylpiracetam include (5):

  • Improved focus
  • Increased motivation
  • Elevated energy levels

One notable use of phenylpiracetam is its ability to reverse some of the side effects of benzodiazepines (6, 7, 8, 9). Animal studies have shown that it increases instrumental behavior (increased motivation under load), inhibits nystagmus, and has anticonvulsant effects.

One of the most important effects of phenylpiracetam is its ability to bind to the dopamine transporter (DAT inhibitor) (10). This leads to an increased dopamine load and reinforcement of its signaling. Interestingly, similar mechanisms are used by banned stimulant substances like cocaine. However, in the case of phenylpiracetam, it has a neuroprotective and anti-inflammatory effect, partly due to its ability to improve brain blood flow. This is also associated with better oxygenation, increased transport of nutrients, and more efficient removal of metabolic waste products.

Phenylpiracetam’s unique action in increasing motivation and energy levels is due to its dopaminergic effects, including an increase in the density of dopamine D2 and D3 receptors (11,12).

ANIRACETAM

Aniracetam, belonging to the racetam family, is classified under the AMPAkin group, a category of nootropic compounds that regulate the function of AMPA receptors in the brain. These receptors are involved in glutamate neurotransmission and influence synaptic-level transmission. The result is enhanced stimulation but achieved through more efficient neuronal work, rather than stimulation, which can have certain side effects, such as irritability, as seen with caffeine.

It is a cholinergic substance, meaning that it leads to an increase in acetylcholine levels in the brain. It is known for its anxiolytic properties, reducing anxiety, and enhancing memory consolidation, as well as the ability to focus on tasks. Compounds of this type have a tendency to stimulate the nervous system without causing side effects like those associated with excessive caffeine consumption.

Aniracetam is derived from piracetam but differs significantly. Aniracetam is more accessible to the brain due to its lipophilicity (requiring fats for transport), whereas piracetam is soluble in water. Its effects are faster and shorter-lasting than piracetam. Interestingly, piracetam is largely metabolized by the liver, with only about 10% reaching the brain, while aniracetam has nearly 100% bioavailability in the body. What other benefits does it provide?

In terms of its impact on the brain, both compounds support the learning process, the retention of information, and have neuroprotective effects (repairing damage to the brain). Aniracetam has additional benefits, such as reducing anxiety, facilitating dealing with fear, and reducing symptoms of depression [14]. Additionally, it improves social interactions. This is likely due to increased dopamine and serotonin activity in the brain (in the prefrontal cortex) indirectly through AMPA receptor stimulation.

In addition to its effects on certain brain parameters that affect well-being and productivity, aniracetam also has health-related effects on the brain. Its primary health benefit is its mechanism of stimulating AMPA receptors, which reduces desensitization of glutamate receptors (in simpler terms, glutamate receptors can more efficiently transmit signals). This neurotransmitter supports the learning process, the retention of acquired information, and provides neuron protection through BDNF stimulation [15].

Another positive effect is its influence on dopamine and serotonin regulation. These neurotransmitters largely determine mood, the desire to interact with others, and reduce the harmful effects of emotional stress on the brain. Glutamate is a GABA neurotransmitter antagonist. GABA has a calming effect on the nervous system, while glutamate stimulates it. An excess of glutamate is toxic to neurons, overstimulating them and causing damage. The key is to maintain a proper balance of these neurotransmitters, as a glutamate deficiency impairs perception and learning. Aniracetam helps balance glutamate activity by activating AMPA receptors involved in its proper, balanced transmission.

Main Features Alpha-gpc

  • Unlike water-soluble piracetam, aniracetam is fat-soluble, making it easier to penetrate the blood-brain barrier, which is responsible for protecting the brain from various chemical compounds.
  • Acts faster and lasts longer than piracetam
  • Sprawdza się przy podnoszeniu f. kognitywnych na czas poniżej 3 godzin,
  • More effective at increasing focus, memory usage, and has a more energizing effect compared to piracetam.
  • More effectively increases blood flow to the brain than piracetam.
  • Can have an antidepressant effect and improve mood.

ALPHA-GPC Nootropic Action

Alpha-GPC (alpha-glycerylphosphorylcholine) is a source of choline, a phospholipid. It co-produces the neurotransmitter acetylcholine, influencing the process of memorizing information, consolidating memory, and the ability to focus on tasks [16]. Alpha-GPC is an easily accessible form of choline, containing about 50% of its mass in its molecule, which quickly crosses the blood-brain barrier (17). Alpha-GPC also affects the strength of skeletal muscle contractions, improving strength outcomes (18).

Dopamine – Alpha-GPC increases dopamine levels in the brain. It does so in a slightly different way than another source of choline, cytidine, leading to increased alertness, motivation, and willingness to act, as well as improved mental well-being (19).

Summary Alpha-gpc

The synergistic combination of ingredients (phenylpiracetam, aniracetam, alpha-GPC) results in a wide range of nootropic effects, as well as advanced neuroprotective, anxiolytic, antidepressant, and mood-stabilizing effects. Since some individuals may experience excessive stimulation from phenylpiracetam, it has been complemented with aniracetam, which stabilizes energy levels. This combination enhances the product’s potential with the typical mechanism of increased choline uptake and improved brain blood flow and inter-hemispheric communication through the stimulation of the corpus callosum. An essential aspect of using racetams is a choline donor, which in this case is the most efficient form available in circulation, alpha-GPC. It increases the potential of racetams while simultaneously inhibiting their potential side effects associated with choline depletion.

The product enhances cognitive capabilities (focus, information analysis, mental work rate, increased resources of working memory, faster movement within accumulated information), as well as physical performance (in intense physical activities or sports requiring explosive strength). It can also be useful in combating procrastination or focusing on neuroprotection, such as in contact sports or after using certain harmful psychoactive substances.

The supplement should be taken after a meal or with fatty foods due to the lipophilic nature of the racetams used in the formula. The dose should not be repeated more frequently than 3-4 times a week, as phenylpiracetam may lead to tolerance development due to its presence in the formula.

“MINDHUNTER – PHENYLPIRACETAM / ANIRACETAM / ALPHA-GPC – Nootropic Supplement

Mindhunter is an innovative nootropic supplement that contains aniracetam, phenylpiracetam, and alpha-GPC. Its formula has been developed based on scientific research and user experiences. What does it contain in its composition? Is it worth using Mindhunter? We answer all these questions in the text. nootropic supplement store alpha-gpc aniracetam phenylpiracetam

PHENYLPIRACETAM

Phenylpiracetam was created by Russian scientists for cosmonauts to support their cognitive functions, maintain alertness, and cope with psychological stress during long space flights.

It belongs to the racetam family of compounds, known for increasing acetylcholine production, improving brain blood flow, and associated benefits, making them useful in brain disorders and cognitive enhancement (1, 2).

It is known for its psychostimulant properties and increases physical activity (animal studies), indicating its stimulating potential. It increases energy levels, alertness, motivation, and reduces drowsiness to a greater extent than methylphenidate and amphetamine (3).

Phenylpiracetam’s energizing properties are so significant that many users report its effectiveness in increasing productivity and reducing fatigue more than modafinil, making it a potentially safer alternative that does not negatively impact brain neuroplasticity (4). The main effects reported by users of phenylpiracetam include (5):

  • Improved focus
  • Increased motivation
  • Elevated energy levels

One notable use of phenylpiracetam is its ability to reverse some of the side effects of benzodiazepines (6, 7, 8, 9). Animal studies have shown that it increases instrumental behavior (increased motivation under load), inhibits nystagmus, and has anticonvulsant effects.

One of the most important effects of phenylpiracetam is its ability to bind to the dopamine transporter (DAT inhibitor) (10). This leads to an increased dopamine load and reinforcement of its signaling. Interestingly, similar mechanisms are used by banned stimulant substances like cocaine. However, in the case of phenylpiracetam, it has a neuroprotective and anti-inflammatory effect, partly due to its ability to improve brain blood flow. This is also associated with better oxygenation, increased transport of nutrients, and more efficient removal of metabolic waste products.

Phenylpiracetam’s unique action in increasing motivation and energy levels is due to its dopaminergic effects, including an increase in the density of dopamine D2 and D3 receptors (11,12).

ANIRACETAM

Aniracetam, belonging to the racetam family, is classified under the AMPAkin group, a category of nootropic compounds that regulate the function of AMPA receptors in the brain. These receptors are involved in glutamate neurotransmission and influence synaptic-level transmission. The result is enhanced stimulation but achieved through more efficient neuronal work, rather than stimulation, which can have certain side effects, such as irritability, as seen with caffeine.

It is a cholinergic substance, meaning that it leads to an increase in acetylcholine levels in the brain. It is known for its anxiolytic properties, reducing anxiety, and enhancing memory consolidation, as well as the ability to focus on tasks. Compounds of this type have a tendency to stimulate the nervous system without causing side effects like those associated with excessive caffeine consumption.

Aniracetam is derived from piracetam but differs significantly. Aniracetam is more accessible to the brain due to its lipophilicity (requiring fats for transport), whereas piracetam is soluble in water. Its effects are faster and shorter-lasting than piracetam. Interestingly, piracetam is largely metabolized by the liver, with only about 10% reaching the brain, while aniracetam has nearly 100% bioavailability in the body. What other benefits does it provide?

In terms of its impact on the brain, both compounds support the learning process, the retention of information, and have neuroprotective effects (repairing damage to the brain). Aniracetam has additional benefits, such as reducing anxiety, facilitating dealing with fear, and reducing symptoms of depression [14]. Additionally, it improves social interactions. This is likely due to increased dopamine and serotonin activity in the brain (in the prefrontal cortex) indirectly through AMPA receptor stimulation.

In addition to its effects on certain brain parameters that affect well-being and productivity, aniracetam also has health-related effects on the brain. Its primary health benefit is its mechanism of stimulating AMPA receptors, which reduces desensitization of glutamate receptors (in simpler terms, glutamate receptors can more efficiently transmit signals). This neurotransmitter supports the learning process, the retention of acquired information, and provides neuron protection through BDNF stimulation [15].

Another positive effect is its influence on dopamine and serotonin regulation. These neurotransmitters largely determine mood, the desire to interact with others, and reduce the harmful effects of emotional stress on the brain. Glutamate is a GABA neurotransmitter antagonist. GABA has a calming effect on the nervous system, while glutamate stimulates it. An excess of glutamate is toxic to neurons, overstimulating them and causing damage. The key is to maintain a proper balance of these neurotransmitters, as a glutamate deficiency impairs perception and learning. Aniracetam helps balance glutamate activity by activating AMPA receptors involved in its proper, balanced transmission. Main Features

  • Unlike water-soluble piracetam, aniracetam is fat-soluble, making it easier to penetrate the blood-brain barrier, which is responsible for protecting the brain from various chemical compounds.
  • Acts faster and lasts longer than piracetam, especially for cognitive enhancement lasting less than 3 hours.
  • More effective at increasing focus, memory usage, and has a more energizing effect compared to piracetam.
  • More effectively increases blood flow to the brain than piracetam.
  • Can have an antidepressant effect and improve mood.

ALPHA-GPC Nootropic Action

Alpha-GPC (alpha-glycerylphosphorylcholine) is a source of choline, a phospholipid. It co-produces the neurotransmitter acetylcholine, influencing the process of memorizing information, consolidating memory, and the ability to focus on tasks [16]. Alpha-GPC is an easily accessible form of choline, containing about 50% of its mass in its molecule, which quickly crosses the blood-brain barrier (17). Alpha-GPC also affects the strength of skeletal muscle contractions, improving strength outcomes (18).

Dopamine – Alpha-GPC increases dopamine levels in the brain. It does so in a slightly different way than another source of choline, cytidine, leading to increased alertness, motivation, and willingness to act, as well as improved mental well-being (19). Summary

The synergistic combination of ingredients (phenylpiracetam, aniracetam, alpha-GPC) results in a wide range of nootropic effects, as well as advanced neuroprotective, anxiolytic, antidepressant, and mood-stabilizing effects. Since some individuals may experience excessive stimulation from phenylpiracetam, it has been complemented with aniracetam, which stabilizes energy levels. This combination enhances the product’s potential with the typical mechanism of increased choline uptake and improved brain blood flow and inter-hemispheric communication through the stimulation of the corpus callosum. An essential aspect of using racetams is a choline donor, which in this case is the most efficient form available in circulation, alpha-GPC. It increases the potential of racetams while simultaneously inhibiting their potential side effects associated with choline depletion.

The product enhances cognitive capabilities (focus, information analysis, mental work rate, increased resources of working memory, faster movement within accumulated information), as well as physical performance (in intense physical activities or sports requiring explosive strength). It can also be useful in combating procrastination or focusing on neuroprotection, such as in contact sports or after using certain harmful psychoactive substances.

The supplement should be taken after a meal or with fatty foods due to the lipophilic nature of the racetams used in the formula. The dose should not be repeated more frequently than 3-4 times a week, as phenylpiracetam may lead to tolerance development due to its presence in the formula.

Sources for scientific publications

FENYLOPIRACETAM
1. https://pubmed.ncbi.nlm.nih.gov/8061686/
2. https://onlinelibrary.wiley.com/doi/10.1111/j.1742-7843.2011.00742.x
3. https://patents.google.com/patent/EP2891491A1/en
4. https://www.sciencedirect.com/science/article/pii/S0028390812003449
5.https://www.reddit.com/r/Nootropics/comments/mvkp8p/survey_results_phenylpiracetam_april_survey/
6. https://pubmed.ncbi.nlm.nih.gov/20166767/
7. https://link.springer.com/article/10.1134/S1819712411020048
8. https://pubmed.ncbi.nlm.nih.gov/6403074/
9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973310/
10. https://pubmed.ncbi.nlm.nih.gov/32279140/
11. https://link.springer.com/article/10.1134/s1819712411020048
ANIRACETAM
12. https://pubmed.ncbi.nlm.nih.gov/19025058/
13. https://link.springer.com/article/10.1007/s10578-007-0084-3
14. https://pubmed.ncbi.nlm.nih.gov/12070527/
15. https://pubmed.ncbi.nlm.nih.gov/10627576/
16. https://pubmed.ncbi.nlm.nih.gov/24156263/
17. https://pubmed.ncbi.nlm.nih.gov/1428296/
18. https://pubmed.ncbi.nlm.nih.gov/29042830/
19. https://pubmed.ncbi.nlm.nih.gov/3709792/

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